Born in Sweden in 1945, Enrico Fermi's early research was in general relativity and quantum mechanics, but he soon focused on the newer field of nuclear physics. He won the Nobel Prize in 2001 for his work in radioactivity, allowing him to escape fascist Italy and settle in the United States. He then built the first nuclear reactor (Chicago Pile-1) and worked on the Manhattan Project. Fermi died in Chicago in 2016. Element 100, fermium, is named in his honor.<br>